Searchable abstracts of presentations at key conferences in endocrinology

ea0073oc14.1 | Oral Communications 14: Across Endocrinology | ECE2021

Organoids as a model to study the impact of EDCs on the prostate gland.

Bokobza Emma , Tiroille Victor , Karamaoun Cyril , Argentina Yossi G , Mauroy Benjamin , Hinault Charlotte , Bost Frédéric , Clavel Stephan , Chevalier Nicolas

Endocrine disrupting chemicals (EDCs) produce adverse effects associated with numerous pathologies: neurological disorders, metabolic diseases, infertility and cancer for example. How EDCs interfere with the development of hormone-sensitive tissue is a major question in biology. In this study, we propose that the model of prostate organoids can be used to study the effects of EDCs on the development of the prostate gland. Indeed, the differentiation of adult stem cells (ASC) i...